Multi-Ethnic Study of Atherosclerosis

Asymptomatic subjects who were healthy (not showing symptoms of cardiovascular disease) during recruitment / imaging.

About

MESA (Multi-Ethnic Study of Atherosclerosis) is a large-scale cardiovascular population study (>6,500 participants) conducted in six centres in the USA. It aims to investigate the manifestation of subclinical to clinical cardiovascular disease before signs and symptoms develop. Since MESA participants were determined as healthy during recruitment, patients of this data are identified as asymptomatic subjects. The overall demographics of the MESA study were men and women aged 45-84 years from heterogeneous US population of White, African-American, Hispanic and Chinese ethnicity.

The Data

 
Image type MRI
Number of cases 2,450
Gender 1,167 Male / 1,251 Female
Age 44 - 84
CINE protocol Gradient Echo (GRE)
Scanner 1.5T (mixed vendor)

Other notes:

All imaging examinations used a four-element phased-array surface coil placed anterior and posterior, ECG gating, and brachial artery blood pressure monitoring. For a subset of the MESA participants (~2,200 cases) 3 tagged short-axis slices were also obtained. Parallel stripe tags were prescribed in 2 orthogonal orientations (0° and 90°) using the same imaging pulse sequence with additional spatial modulation of magnetization encoding gradients.

Number of cases 1,861 (75.96%)
Analysis Manual contouring
Frames End-Diastole and End-Systole
View Short-axis images
Software used QMass
Type Endocardium and epicardium
File format JSON

Data Contributors

Dr. David A. Bluemke, MD
National Institutes of Health, USA
Dr. Joao Lima, MD
John Hopkins University, USA